Interactions Between Retroviruses And Herpesviruses

Retroviruses and herpesviruses are two common human pathogens. Co-infections of these two viruses in the same individuals are frequently observed, especially in patients afflicted with AIDS. Potential consequences of such interactions include the exacerbration of the disease, changing the disease courses and the release of new viruses. Understanding the underlying mechanism is important, but, thus far, few insights have been gained. The present monograph is intended to provide an updated and concise review of recent work regarding the molecular and cellular mechanisms of such interactions. The topics covered range from transcriptional regulation, receptor modulation and genetic recombination to AIDS and oncogenesis. Human immunodeficiency virus, avian leukosis virus, reticuloendotheliosis virus, herpes simplex virus, cytomegalovirus, herpesvirus-6 and Marek's disease virus are among the viruses discussed. The contributing authors are among the leaders in this field and responsible for many of the original discoveries presented. The presented book should serve as a valuable research and teaching reference for both beginning and advanced researchers in virology and oncology.