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This book comprises of two research paper one is on MRSA TYPING and another one is DRUG DESIGNING.Methicillin Resistant Staphylococcus aureus is vulnerable in our society. This research work is a prove that MRSA outbreak is rapidly spreading among the patients and detailed analysis of MRSA has been conducted in various stages. Another research work which has been conducted is Drug Designing of Tuberculosis. Different bioinformatics tools have been used to create different ligands which can bind to the protein. Thus in various stages, it has been proved that one of the ligands is compatible to bind with the protein.